NEW YORK GIANTS (3-3) vs LOS ANGELES (3-3) at London
Sunday, 9:30 a.m. EDT, CBS
OPENING LINE — Giants by 2 1/2
RECORD VS. SPREAD — New York 1-3-2, Los Angeles 3-2-1
SERIES RECORD — Rams lead 25-15
LAST MEETING — Giants beat Rams 37-27, Dec. 21, 2014
LAST WEEK — Giants beat Ravens 27-23; Lions beat Rams 31-28
AP PRO32 RANKING — Giants No. 16, Rams No. 20
GIANTS OFFENSE — OVERALL (13), RUSH (30), PASS (3).
GIANTS DEFENSE — OVERALL (19), RUSH (12), PASS (22).
RAMS OFFENSE — OVERALL (31), RUSH (28), PASS (28).
RAMS DEFENSE — OVERALL (17), RUSH (23), PASS (16).
STREAKS, STATS AND NOTES — London calls teams from two biggest U.S. cities for first NFL game at Twickenham Stadium, ancestral home of English rugby. … Giants haven’t been to England since 2007, when they beat Miami in first NFL regular-season game outside North America. … Giants have won seven straight over Rams since 2002. QB Eli Manning has never lost to Rams. … WR Odell Beckham Jr. didn’t practice Wednesday (hip pointer) and might not be available. He had eight catches for 148 yards and two TDs vs. Rams as rookie in 2014. … Giants defensive coordinator Steve Spagnuolo went 10-38 as St. Louis Rams head coach from 2009-11. Jeff Fisher succeeded him. … Giants quarterbacks coach Frank Cignetti Jr. was Rams offensive coordinator last season until Fisher fired him Dec. 7 with offense ranked last in NFL. … Giants relying heavily on passing game that has outgained running game 1,788-456. Rams have been solid against pass, but top CB Trumaine Johnson is out with injury. … Johnson played last season alongside Giants CB Janoris Jenkins, who left Rams this spring for lavish free-agent deal in New York. He leads Giants with two interceptions. … During homecoming relocation season, Rams also must travel NFL-high 37,092 miles for games outside LA. … Rams haven’t played internationally since 2012. … Rams are nominal “home” team, preventing LA from seeing Giants for first time since 1994. … Rams’ offense rocketed up from 32nd to 31st in NFL standings last weekend with 387 yards at Detroit. Rams had NFL’s worst offense last season and again for most of this fall. … QB Case Keenum is coming off best game of season, going 27 for 32 with 321 yards, three TDs and franchise-record 19 straight completions. Wasn’t enough to beat Lions. … Rams DL coach Mike Waufle had same job with Giants from 2004-09. … Fantasy Tip: RB Todd Gurley still can’t get going. He has 346 yards in six games with just 2.9 per carry — lowest in NFL among backs with 50 carries.